Table 7.

Top-cited research articles in gastroenterology and hepatology identified by searching gastroenterology and hepatology journals (list A) or by searching keywords for all journals listed in the Web of Science (list B): by article topic and research type*

Topic	Research type: number of articles (references)
	Cross-sectional study	Case–control study	Cohort study	Randomised controlled trial	Experimental study	Causal-comparative study
Gastro-oesophageal reflux disease	157
Gastritis, gastric ulcer, Helicobacter pylori			292 118		245 88
Prostaglandins and gastric protection						137
Functional gastrointestinal disorders	156
Escherichia coli and diarrhoeal disease					286 96
Chemotherapy and gastrointestinal toxicity				1107
Pancreatic cancer				194
Intestinal ischaemia						165
Inflammatory bowel disease				1111	660 68 87 91 99 113	229 61
Colorectal cancer		133	2105 106	679 95 104 114 116 117	351 100 109
Stromal tumours
Chronic hepatitis and viral hepatitis			458 73 78 90	482 83 98 115	326 36 80
Fatty liver disease	248 62		142		130
Oesophageal varices			181
Bilirubin and hepatic transporters					1108
Haemochromatosis					197
End-stage liver disease and liver failure					134	171
Hepatocellular carcinoma			289 119	272 84	154
Total	4	1	12	15	21	5

*The research papers^{26 29 30 33} were identified in lists A and B and each was recorded once only in this table.