Table 5. Associations between regional cerebrovascular disease and regional amyloid uptake measured as PET SUVR for CHE, SCD and MCI subjects.

Group	Parameter	ARWMC frontal			ARWMC parito-occipital			ARWMC temporal
CHE, SCD, MCI	Frontal SUVR	0.088	−0.027	0.203	0.079	−0.036	0.194	0.140*	0.022	0.259
	Parietal SUVR	0.119	0.004	0.233	0.117	0.002	0.231	0.168**	0.050	0.285
	Occipital SUVR	0.097	−0.018	0.213	0.092	−0.023	0.207	0.148*	0.029	0.266
	Temporal SUVR	0.061	−0.053	0.175	0.055	−0.059	0.168	0.104	−0.014	0.221

Values represent standardized beta from linear regression with regional ARWMC as dependent and regional amyloid uptake as independent variable as well as the confidence intervals, and are corrected for age, sex and hippocampal volume. Cerebrovascular disease was estimated as the total score of white matter lesion rating according to the ARWMC scale, total sum, and regional, mean of left and right. PET SUVR was estimated the regional uptake, mean of left and right; the natural logarithm of PET estimates was used.

*p < 0.05, **p < 0.0125, ***p > 0.001.

Only p-values < 0.0125 should be considered significant according to Bonferroni-adjustment.