Skip to main content
. 2016 Feb 9;6:20756. doi: 10.1038/srep20756

Table 1. General Characteristics of the Included Studies.

First author Year Location Race Mean/median age (range) (y) Gender (M/F) Case (n)
Control (n)
Method Control style Control source
M+ U M+ U
Hogg34 2002 UK Caucasians NA NA 4 24 0 24 BSP A NMT
Dong26 2003 USA Caucasians NA NA 7 46 0 46 MSP A ANT
Maruya22 2004 USA Caucasians 58 (31–81) 26/6 0 32 1 32 MSP A NMT
Xu23 2006 China Asians 60 (41–76) 35/13 34 48 11 48 MSP A ANT
Righini27 2007 French Caucasians 57 (33–74) NA 14 90 0 30 MSP A NMT
Wan31 2007 China Asians NA 17/15 13 32 4 28 MSP H OCT
                0 10 MSP H OCT
Ghosh33 2008 India Asians NA NA 23 111 9 52 MSRA H DLT
Steinmann28 2009 Germany Caucasians 57 (41–77) NA 10 54 0 23 MSP A CMT
Su24 2010 Taiwan Asians 55 (37–82) 47/5 9 31 12 31 Q-MSP A ANT
                0 12 Q-MSP H NMT
Laytragoon-Lewin29 2010 Sweden Caucasians 62 (42–101) 30/11 8 18 4 18 MSP A NMT
Paluszczak30 2011 Poland Caucasians 58 (41–75) 35/6 13 41 9 41 MSP A NMT
Koutsimpelas31 2012 Germany Caucasians 62 (45–83) 19/4 3 23 0 3 MSP H GT

Abbreviation: NA, not available; M, male; F, female; M+, methylated; U, unmethylated; A, Autologous (the control from the HNSCC patients themselves); H, Heterogeneous (the control from other individuals); NMT, normal mucosa tissue; ANT, adjacent non-tumor tissue; OCT, oral cavity tissue; DLT, dysplastic lesions tissue; CMT, cheek mucosa tissue; GT, gingiva tissue.