Skip to main content
. 2016 Feb 9;6:20630. doi: 10.1038/srep20630

Figure 3. SNX10 deficiency increases the population of M2-type macrophages and decreases pro-inflammatory cytokine expression in colonic tissues.

Figure 3

(A) Colonic tissue sections from normal control groups and DSS-induced colitis groups were stained respectively with anti-F4/80 and anti-CD206 antibodies to detect macrophage subpopulations (×10). The ratio between CD206+ and F4/80+ cells was calculated. (B) FACS analysis of macrophage subsets in colonic tissues of mice with DSS-induced colitis. The percentage of CD206+ cells in F4/80+ cells were calculated and shown as means ± SEM (n = 6 in each group). (C) The expression of pro-inflammatory cytokines in colonic tissues was determined by RT real-time -PCR. *P < 0.05, **P < 0.01, ***P < 0.001 vs WT normal control group. ##P < 0.01, ###P < 0.001 vs WT with DSS induction group.