. 2016 Feb 9;6:20647. doi: 10.1038/srep20647

Table 4. Association of RA with depression stratified by sex, age, and follow-up years.

Variables	Non-depression cohort			Depression cohort			HR (95% CI)
Variables	Case	PYs	Incidence	Case	PYs	Incidence	Crude	Adjusted
All	837	692396.22	1.21	718	347046.11	2.07	1.71 (1.55–1.89)	1.65^* (1.41–1.77)
Sex
Female	664	416464.90	1.59	560	209084.69	2.68	1.68 (1.50–1.88)	1.55^ξ (1.34–1.74)
<=40	90	144727.65	0.62	98	72211.49	1.36	2.18 (1.64–2.91)	1.95^Υ (1.37–2.48)
41–60	317	169788.73	1.87	299	84961.55	3.51	1.89 (1.61–2.21)	1.62^Υ (1.38–1.93)
60⁺	257	101948.51	2.52	163	51911.65	3.14	1.24 (1.02–1.51)	1.19^Υ (0.98–1.47)
Male	173	275931.32	0.63	158	137961.42	1.15	1.83 (1.47–2.26)	1.61^ξ (1.28–2.02)
<=40	20	94640.07	0.21	25	47264.23	0.52	2.50 (1.39–4.51)	2.04^Υ (1.09–3.86)
41–60	71	101874.80	0.70	67	50937.94	1.32	1.89 (1.35–2.64)	1.61^Υ (1.13–2.28)
60⁺	82	79416.45	1.03	66	39759.25	1.66	1.60 (1.16–2.21)	1.40^Υ (0.99–1.96)
Follow-up (years)
≦2	245	9526.52	25.72	204	4892.39	41.69	1.62 (1.35–1.96)	1.47^* (1.14–1.76)
3–5	156	49293.82	3.16	153	25200.05	6.07	1.94 (1.54–2.40)	1.83^* (1.61–2.19)
>5	436	633575.88	0.68	361	316953.66	1.14	1.66 (1.44–1.91)	1.58^* (1.34–1.79)

Incidence rate is per 1,000 PYs.

^ΥModel adjusted for urbanization level, monthly income, and comorbidity

^ξModel adjusted for age, urbanization level, monthly income, and comorbidity.

^*Model adjusted for age, gender, urbanization level, monthly income, and comorbidity.