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. 2016 Feb 9;6:20510. doi: 10.1038/srep20510

Figure 4. Evolutionary scenario of LC-PUFA biosynthesis functional diversification in Bilateria.

Figure 4

(A) PUFA elongase substrate preference in octopus, amphioxus, lamprey, elephant shark, zebrafish, chicken and human; (B) schematic view of gene duplication events in the elongation/desaturation network along the invertebrate/vertebrate transition (top left) and known enzymatic activities of FADS and ELOVL (right; from top to bottom: octopus, amphioxus, lamprey and the gnathostomes elephant shark and human); Δ5 and Δ6 denote desaturation activities.