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. 2016 Feb 9;6:20587. doi: 10.1038/srep20587

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(A) The mixture of anti-αv (5 μg/mL) and anti-β3 (5 μg/mL) integrin antibodies partially decreased the POSTN-inducing (100 ng/mL) proliferation of HN13 and Rca-T cells. (B,C) Recombinant human POSTN (100 ng/mL) promoted the migration and invasion of HNC cells (HN13 and Rca-T), while blocking of αv and β3 integrins by integrin antibodies (5 μg/mL of each) inhibited the migration and invasion of HNC cells (HN13 and Rca-T) cultured in DMEM with 100 ng/mL POSTN. (*p < 0.05; **p < 0.01; ***p < 0.001).