Figure 3.

SEND1 and MUS81 Play Overlapping Roles in Preserving Genome Stability.

(A) Distribution of mitotic nuclear DNA contents in 1-week-old seedlings of wild-type, send1, mus81, and mus81 send1 mutant plants determined by flow cytometry. Percentage of nuclei in each category is indicated.

(B) and (C) Mean fraction (±se) of EDU+ nuclei (n = 5) (B) and mean (±se) number of dead cells per root tip (n = 12) (C) in wild-type, send1, mus81, and mus81 send1 mutant plants. Individual values are shown as filled diamonds. Cell cycle is affected in mus81 send1 mutant plants as shown by reduced EdU incorporation and spontaneous cell death.