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mus81 send1 Double Mutants Accumulate DSBs, Which Are Enriched in Replicating Cells.
(A) γ-H2AX (green) foci in S- or early G2-phase (EdU+; magenta) mitotic nuclei of mus81 send1 plants. Bar = 2 µm.
(B) Mean (±se) numbers of γ-H2AX foci per nucleus in total nuclei (black fill) or EdU-positive nuclei (gray fill) of wild-type, send1-1, mus81, and mus81 send1 mutants (n = 100 for total nuclei and n = 50 for EdU-positive nuclei).
