Figure 6.

Telomere Instability and Chromosome Fusions in mus81 send1.

(A) TRF analysis of bulk telomere length in genomic DNA using the telomeric repeat probes. G2 and G3 indicate second and third mutant generations.

(B) Percentages of mitotic anaphases with at least one visible chromosome bridge in wild-type and mutant plants (n = number of anaphases counted).

(C) Examples of mus81 send1 mitotic anaphases showing chromosome bridges analyzed by FISH with a pool of nine subtelomeric BAC fluorescent probes (magenta). DNA is counterstained with DAPI (blue). Bar = 10 µm.