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. Author manuscript; available in PMC: 2016 Feb 9.
Published in final edited form as: J Neurosurg. 2013 Apr 26;119(2):427–433. doi: 10.3171/2013.3.JNS122226

Fig. 3. Anaplastic astrocytoma (Case 3).

Fig. 3

A: Preoperative T1-weighted MR image showing an enhancing Grade III glioma. B: An H & E–stained specimen showing a very hypercellular lesion. C: Immunostained specimen showing diffuse GFAP (green) staining with loss of the tight organization of GFAP filaments around the red CD31-positive vessels. D: Specimen stained for AQ4 (red) also showing diffuse staining with no strong border formed around the CD31-positive vessels (green).