Table 4.
GO function terms were enriched within genes with hypermethylated a-CpGs in the analysis with GOrilla. Table contains the full list of enriched GO function terms (Bonferroni-adjusted p < 0.05) obtained from analysis with GOrilla [21, 43]
GO term | Description of the function | p-value (-log10) |
---|---|---|
GO:0043565 | Sequence-specific DNA binding | 10.001 |
GO:0000981 | Sequence-specific DNA binding RNA polymerase II transcription factor activity | 7.322 |
GO:0001071 | Nucleic acid binding transcription factor activity | 6.721 |
GO:0003700 | Sequence-specific DNA binding transcription factor activity | 6.721 |
GO:0003677 | DNA binding | 6.625 |
GO:0005326 | Neurotransmitter transporter activity | 5.148 |
GO:0005488 | Binding | 4.967 |