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. 2016 Feb 9;17:76. doi: 10.1186/s12859-016-0913-0

Table 3.

Stability tests of α, n, π i and the relative weights of the structural penalties

Default setting n=25,π i=0.5i n=50,π i=0.5i n=75,π i=0.5i π i=0.25i, n=50 π i=3i, n=50
0.41 0.41 0.41 0.41 0.42
Default setting α=10−5 α=10−2 α=10−3 α=10−4 α=10−6
0.41 0.37 0.40 0.41 0.42
Default setting g4=2.0 g4=0.0 g4=1.0 g4=5.0 g4=10.0
0.41 0.39 0.41 0.41 0.41
Default setting r=25.0 r=0.0 r=1.0 r=15.0 g=35.0
0.41 0.36 0.38 0.41 0.41
Default setting a=25.0 a=0.0 a=50.0 a=75.0 a=100.0
0.41 0.40 0.41 0.41 0.41

The average AUPR score on a subset of 15 GENIE3 predictions is shown and compared to the score using default settings. Parameters not listed were set to default values. (g4 = graphlet, r = regulatory, a = anti-dominating)