Table 3.
Body weight (g) of individual mice
Laparotomy groups |
Analgesic-only groups |
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Time (h) | Mouse no. | Saline | Bup-HCl | Bup-SR | Bup-HCl | Bup-SR |
0 | 1 | 29.3 | 28.6 | 22.6 | 26.2 | 29.0 |
2 | 30.2 | 27.0 | 25.5 | 25.9 | 24.6 | |
3 | 27.5 | 25.5 | 22.8 | 22.9 | 24.8 | |
4 | 29.0 | 29.0 | 28.5 | 26.3 | 26.1 | |
5 | 30.7 | 29.8 | 31.4 | 29.9 | 26.0 | |
6 | 30.4 | 27.4 | 31.3 | 31.6 | 24.2 | |
7 | 28.5 | 27.1 | 29.4 | 28.5 | 27.4 | |
mean ± 1 SD | 29.4 ± 1.2 | 27.8 ± 1.5 | 27.8 ± 3.6 | 27.3 ± 2.9 | 26.0 ± 1.7 | |
24 | 1 | 27.5 | 26.4 | 21.3 | 26.2 | 23.8 |
2 | 27.2 | 23.4 | 23.4 | 25.3 | 24.4 | |
3 | 26.6 | 25.5 | 22.0 | 23.6 | 24.0 | |
4 | 27.3 | 27.5 | 27.2 | 25.6 | 25.4 | |
5 | 28.4 | 29.2 | 28.6 | 29.1 | 25.1 | |
6 | 29.6 | 29.2 | 25.4 | 29.6 | ND | |
7 | 27.1 | 22.3 | 25.6 | 27.2 | 27.1 | |
mean ± 1 SD | 27.7 ± 1.0 | 26.2 ± 2.7 | 24.8 ± 2.7 | 26.7 ± 2.1 | 24.9 ± 1.2 | |
48 | 1 | 26.5 | 26.8 | 21.7 | 26.9 | 28.4 |
2 | 25.9 | 22.4 | 21.5 | 25.2 | 24.8 | |
3 | 27.4 | 24.8 | 20.5 | 23.8 | 25.0 | |
4 | 28.3 | 26.0 | 26.6 | 25.5 | 25.5 | |
5 | 29.5 | 28.8 | 29.2 | 29.3 | 25.5 | |
6 | 29.1 | 26.2 | 29.1 | 30.7 | 23.9 | |
7 | 28.0 | 26.1 | 28.3 | 27.7 | 28.9 | |
mean ± 1 SD | 27.8 ± 1.3 | 25.9 ± 1.9 | 25.2 ± 3.9 | 27.0 ± 2.4 | 26.0 ± 1.9 | |
72 | 1 | 26.9 | 27.3 | 22.2 | 27.3 | 28.9 |
2 | 25.7 | 22.1 | 20.6 | 25.2 | 25.3 | |
3 | 27.3 | 23.8 | ND | 23.9 | 26.9 | |
4 | 28.4 | 25.1 | 26.7 | 26.4 | 26.0 | |
5 | 29.1 | 28.5 | 30.3 | 29.7 | 26.1 | |
6 | 28.7 | 27.3 | 29.4 | 31.6 | 24.3 | |
7 | 28.3 | 24.8 | NDa | 27.2 | 27.2 | |
mean ± 1 SD | 27.7 ± 1.2 | 25.6 ± 3.9 | 25.8 ± 4.3 | 27.3 ± 2.6 | 26.4 ± 1.5 |
ND, not done
Body weight did not change significantly in any group.
Mouse died