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Characterization of PLGA-PEI microparticles
| Size | 1.18 ± 0.28 μm | |
| Zeta potential | 34.13 ± 3.85 mV | |
| Single loading (1.2 wt% nucleic acid to particle ratio) | CpG/IL10-siRNA/Poly(I:C)/pDNA | 12 ug/mg of microparticles (100% loading) |
| Dual loading (1.2 wt% nucleic acid to particle) | CpG + IL10-siRNA/CpG+Poly(I:C) | 6+6 ug/mg of microparticles (100% loading) |
| Triple loading (1.2 wt% nucleic acid to particle ratio) | CpG +IL10-siRNA+pDNA/ CpG+Poly(I:C)+pDNA | 4+4+4 ug/mg of microparticles (100% loading) |
