Table 3.

Occurrence of intracranial hemorrhagic transformation on gradient-recalled echo (GRE)

	Rosuvastatin (n = 137)	Placebo (n = 152)	P value
HI1	2 (1.4)	15 (9.9)	0.002
HI2	2* (1.4)	7† (4.6)	0.177
PH1	1 (0.7)	0 (0.0)	0.478
PH2	0 (0.0)	0 (0.0)
Radiological subarachnoid hemorrhage	1 (0.7)	0 (0.0)	0.478
Any hemorrhagic transformation	6 (4.3)	22 (14.5)	0.007

Values are number (%).

Hemorrhagic transformation was categorized into small petechial hemorrhagic infarction (HI1), confluent petechial HI (HI2), small parenchymal hemorrhage (PH1, <30% of infarct, mild mass effect), and large PH (PH2, >30% of infarct, marked mass effect).[17]

^*including 1 patient who had HI-1 on baseline GRE and HI-2 on follow-up GRE.

^†including 1 patient who had HI-1 on baseline GRE and HI-2 on follow-up GRE, 4 patients who had HI-1 on 5-day GRE and HI-2 on 14-day GRE.