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Sequence and structure of chimeras. (A) Sequence comparison between ASIC2a, ASIC2b, ASIC1a, ASIC1b, ASIC3, and ASIC4 of the region exchanged in AB5; greyness indicates percentage identity. (B) Sequence comparison between ASIC2a, ASIC2b, AB11-4, AB11-5, AB11-6, and ASIC1a; greyness indicates percentage identity. (C) Overview of ASIC2 structure indicating regions swapped in chimera experiments.
