Table I. Description of Basic Characteristics in the CARe Cohorts: Mean ± Standard Deviation or Percentage Unless Otherwise Mentioned.
| Phenotypes | ARIC EA | ARIC AA | CARDIA EA | CARDIA AA | CHS EA | CHS AA | MESA EA | MESA AA | FHS |
|---|---|---|---|---|---|---|---|---|---|
| Total Na | 9,050 | 2,800 | 801 | 484 | 3,830 | 175 | 2,270 | 1,588 | 2,605 |
| Age, years | 54.1 ± 5.7 | 53.2 ± 5.8 | 25.8 ± 3.2b | 24.4 ± 4.0b | 72.8 ± 5.6 | 72.7 ± 5.6 | 62.7 ± 10.3 | 62.2 ± 10.1 | 54.4 ± 9.7 |
| Age range | 44–66 | 44–66 | 18–32b | 17–34b | 65–100 | 65–88 | 44–84 | 45–84 | 26–82 |
| Female (%) | 54.9 | 63.4 | 52.4 | 59.5 | 56.4 | 64.0 | 52.3 | 54.2 | 54.6 |
| FVIII:C (%) (N) | 125 ± 34 (9,041) | 146 ± 46 (2,799) | 93 ± 28 (780) | 106 ± 38 (458) | 121 ± 37 (3,830) | 140 ± 44 (175) | 95 ± 36 (2,270) | 108 ± 43 (1,588) | NA |
| Median FVIII: C, % (IQR) | 121 (101–143) | 140 (114–170) | 90 (74–109) | 101 (78–129) | 116 (95–141) | 134 (106–166) | 90 (70–114) | 101 (77–132) | NA |
| VWF: Ag, % (N) | 111 ± 42 (9,045) | 133 ± 55 (2,799) | 97 ± 32 (799) | 111 ± 44 (483) | NA | NA | 134 ± 54 (414) | 157 ± 63 (178) | 126 ± 45 (2,605) |
| Median VWF: Ag, % (IQR) | 104 (81–133) | 124 (92–164) | 94 (74–115) | 102 (80–134) | NA | NA | 123 (95–166) | 147 (115–199) | 120 (91-156) |
EA = European American, AA = African American, NA = phenotype not available; IQR = interquartle range.
a
overall N available for the analysis of FVIII:C or VWF:Ag.
b
Age at baseline.