. 2015 Sep 22;6(39):42008–42018. doi: 10.18632/oncotarget.5788

Table 1. Factors associated with PFS in patients treated with targeted therapies.

Factor	Variable	Univariate analysis*			Multivariate analysis*
Factor	Variable	p-value	HR	CI (95%)	p-value	HR	CI (95%)
ctDNA	<10 or >=10 copies/ml	*0.017*	*6.34*	*1.38-29.12*	*0.027*	*5.79*	*1.22-27.4*
Age	Continuous	*0.046*	*0.97*	*0.93-0.99*	0.248	0.97	0.93-1.02
Sex	Male vs. Female	0.392	0.78	0.43-1.39	0.548	0.81	0.42-1.59
LDH	Elevated vs. Not elevated	0.848	1.16	0.26-5.27	0.704	0.72	0.14-3.81
Stage	M1a,b vs. M1c	0.356	0.62	0.22-1.72	0.741	0.82	0.26-2.59

Univariate and multivariate Cox regression analysis