Table 2. Different polymer/drug ratio impact on DLE and DLC of drug-loaded NPs.
Nanoparticles | Polymer:CDDP:PTX ratio in Co-FA-NPs | CDDP-FA-NPs | PTX-FA-NPs | Co-NPs (CDDP:PTX=1:2) |
||
---|---|---|---|---|---|---|
40:2:1 | 40:2:2 | 40:2:4 | ||||
DLE of CDDP (%) | 62.43±1.36 | 59.84±0.71 | 49.67±0.98 | 76.92±1.11 | - | 51.24±1.78 |
DLE of PTX (%) | 71.71±1.08 | 66.35±1.83 | 58.46±0.38 | - | 79.49±0.76 | 59.73±0.94 |
DLC (%) | 7.58±0.29 | 11.09±0.41 | 12.07±0.21 | 4.68±0.07 | 5.83±0.04 | 12.41±1.42 |