Table 4. Blood component changing following various drugs treatments.
| Groups | WBC (×109/L) | Neutrophils (×109/L) | Erythrocyte (×1012/L) | Plateletes (×109/L) | ALT (U/L) | AST (U/L) | Scr (μmol/L) | BUN (mmol/L) |
|---|---|---|---|---|---|---|---|---|
| Control | 5.81±1.47 | 1.15±0.26 | 10.14±0.87 | 498.78±78.64 | 28.26±8.46 | 20.71±2.23 | 132.62±19.87 | 6.81±2.11 |
| Free-CDDP | 5.57±2.13 | 0.98±0.14 | 10.53±1.77 | 463.27±91.43 | 31.17±11.32 | 22.63±1.44 | 167.42±21.36 | 8.24±3.45 |
| Free-PTX | 5.21±0.68 | 1.03±0.11 | 9.92±2.14 | 521.27±68.97 | 34.53±6.99 | 23.45±2.02 | 131.56±18.03 | 5.97±1.48 |
| CDDP-FA-NPs | 5.79±1.12 | 1.16±0.23 | 11.06±0.41 | 494.99±104.71 | 26.51±5.43 | 20.24±2.98 | 138.75±24.46 | 6.43±0.79 |
| PTX-FA-NPs | 5.64±1.89 | 1.08±0.09 | 9.87±0.78 | 502.41±64.32 | 30.11±13.71 | 21.12±1.47 | 123.33±15.23 | 7.44±2.87 |
| Co-NPs (CDDP: PTX = 1:2) | 5.51±1.32 | 1.05±0.18 | 10.02±2.14 | 540.65±89.39 | 34.87±6.99 | 22.95±3.26 | 153.72±16.33 | 6.94±1.31 |
| Co-FA-NPs (CDDP: PTX = 1:2) | 5.62±0.47 | 1.32±0.20 | 10.32±1.01 | 537.16±88.08 | 31.76±6.34 | 19.47±1.78 | 137.82±13.67 | 6.12±1.89 |
| Free-CDDP+Free-PTX | 4.26±1.43* | 0.76±0.18* | 9.89±0.93 | 401.3±141.73 | 44.92±10.49* | 28.89±1.23* | 226.54±31.24* | 10.75±3.64* |