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. 2015 Nov 3;6(39):42183–42196. doi: 10.18632/oncotarget.5619

Figure 3. Inhibition of PI3K pathway does not influence signaling or cell growth.

Figure 3

A. KNS-62 and NCI-H1915 cells were treated with 500nM of AZD6244, MEK162 and BKM120 or combinations thereof as indicated for 1 h. Then, cells were lysed and analysed by Western blot. B. KNS-62, NCI-H1915, T24 and RL95–2 cells were left untreated or treated with indicated concentrations of MEK162 and BKM120 for 96 hours. Next, cell growth was measured by Cell Titer Glo according to the manufacturer's instructions. CIs are indicated.