Table 4. Multivariate analysis for PFS and OS using Cox regression model.
| RR | 95% CI | P value | ||
|---|---|---|---|---|
| PFS | MIPI | 1.6 | 0.9–3.0 | .135 |
| Deletion 13q | 1.1 | 0.5–2.8 | .761 | |
| Deletions 17p | 2.5 | 1.1–5.9 | .039 | |
| MYC abnormality | 3.1 | 1.2–7.8 | .020 | |
| Any cytogenetic aberration* | 0.9 | 0.3–3.5 | .923 | |
| OS | Deletions 13q | 0.9 | 0.4–2.3 | .829 |
| Deletions 17p | 2.4 | 1.02– 5.8 | .045 | |
| MYC abnormality | 3.21 | 1.15–8.96 | .026 | |
| Any cytogenetic aberration* | 2.5 | 0.5–12.3 | .257 | |
| CHOP/CHOP-like ± R Treatment | .831 | 0.5–2.5 | .831 | |
Abbreviation: MIPI, MCL international prognostic index; PFS, progress-free survival; OS, overall survival.
*
indicate patients with either del 13q/11q/17p,or BCL2/MYC aberration.