Table 1.

Demographics and results

Bilirubin (mg/dl)
Measure	≤0.5 (n=186)	0.6–0.8 (n=287)	0.9– 1.9 (n=281)	p
Age (years)	54 ± 16	55±17	54±15	0.1
Female	46%	49%	59%	0.0071
White	84%	90%	82%	0.18
Black	15%	9%	16%
Body mass index (kg/m2)	28 ± 8	29 ±4	30 ±7	0.011
Albumin (g/dl)	3.5 ± 0.6	3.4 ±0.6	3.2 ±0.6	0.15
Hematocrit (%)	29 ± 6	28 ±5	27 ±5	0.0062
Prior coronary artery disease/myocardial infarction	11%	12%	13%	0.92
Prior diabetes mellitus	15%	18%	14%	0.37
Prior hypertension	35%	38%	48%	0.009
On angiotensin converting enzyme inhibitor	9%	9%	6%	0.23
On angiotensin receptor blocker	2%	4%	4%	0.47
On β-blocker	9%	6%	7%	0.52
On statin	15%	13%	11%	0.51
Pre-anthracycline-based chemotherapy left ventricular ejection fraction (%)	59.5 ± 7.0	58.9 ±6.7	58.1 ±7.2	0.10
Doxorubicin equivalent (mg/m2)	392 ± 180	408 ±230	406 ±165	0.70