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. 2015 Oct 19;6(38):40704–40718. doi: 10.18632/oncotarget.5727

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Copyright: © 2015 Hussain et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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A, B. Data from GSE2658 (n = 542) were divided based on therapeutic trial (TT2 v. TT3) and were placed into cohorts of UCHL1LO (0–74th percentile) and UCHL1HI (75–100^th percentile). The overall disease-related survival was estimated using the Kaplan-Meyer method. C, D. Progression free survival was estimated for patients with myeloma expressing low UCHL1LO (0–74th percentile) and UCHL1HI (75–100^th percentile), treated with dexamethasone (C) or bortezomib (D) on the APEX trial (GSE9782; only those patients on APEX). E, F. Data as from C, E analyzed according to treatment in UCHL1LO (E) of UCHL1HI cases. In all panels, p values were calculated with the Mantel-Cox log rank test.