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. 2015 Oct 22;6(38):40719–40733. doi: 10.18632/oncotarget.5825

Figure 4. Inhibition of ATM and NF-κB activation abrogates the effect of IL-6 on cell migration in lung cancer cells.

Figure 4

To investigate the role of ATM, NF-κB and MMP-3/MMP-13 in IL-6 increasing cell migration, the indicated cells were performed siRNA transfection a, c, d. or kinases inhibitor treatment b. and cell migration was determined by Transwell migration assay. The data are presented as the mean ± SEM, n = 3. ***p < 0.001, One-way ANOVA with post Newman-Keuls test. One representative from three experiments is shown. CGK733 and BAY11–7082 were shown as CGK and BAY, respectively, for limited space in the figure.