Table 1. Clinical and molecular characteristics.
Variable Total (n, %) | GBM 274 | |
---|---|---|
Age, years | Median (range) | 48 (18–81) |
Age ≥45 | 166 (61) | |
Age <45 | 108 (39) | |
Gender | Male | 169 (62) |
Female | 105 (38) | |
Preoperative KPS score | Preoperative KPS ≥80 | 149 (54) |
Preoperative KPS <80 | 125 (46) | |
Resection | Gross total resection | 163 (59) |
Subtotal | 111 (41) | |
Postoperative Treatment | RT plus TMZ | 229 (84) |
RT only | 45 (16) | |
IDH1/2 mutation | Mutation | 56 (20) |
Wildtype | 209 (76) | |
NA | 9 (3) | |
MGMT promoter methylation | Methylated | 95 (35) |
Not methylated | 143 (52) | |
NA | 36 (13) |