Table 1. Correlation between WWP1 expression and clinicopathological variables of 149 patients with hepatocellular carcinoma.
Clinicopathologic variable | Number in each group | WWP1 expression | P | |
---|---|---|---|---|
Low | High | |||
All cases | 149 | 54 | 95 | |
Age (years) | 0.879 | |||
<50 | 84 | 30 | 54 | |
≥50 | 65 | 24 | 41 | |
Sex | ||||
Male | 122 | 44 | 78 | 0.924 |
Female | 27 | 10 | 17 | |
Tumor size (cm) | 0.015a | |||
<5 | 66 | 31 | 35 | |
≥5 | 83 | 23 | 60 | |
Histological grade | <0.001a | |||
Well | 26 | 19 | 7 | |
Moderate | 94 | 28 | 66 | |
Poor | 29 | 7 | 22 | |
Liver cirrhosis | 0.668 | |||
No | 25 | 10 | 15 | |
Yes | 124 | 44 | 80 | |
HBV | 0.660 | |||
Negative | 16 | 5 | 11 | |
Positive | 133 | 49 | 84 | |
Serum AFP (μg/L) | 0.223 | |||
<25 | 82 | 42 | 40 | |
≥25 | 67 | 41 | 26 | |
TNM stage | <0.001a | |||
I | 91 | 43 | 48 | |
II–III | 58 | 11 | 47 | |
Vascular invasion | 0.018a | |||
No | 131 | 52 | 79 | |
Yes | 18 | 2 | 16 | |
Tumor capsule | 0.026a | |||
No | 76 | 21 | 55 | |
Yes | 73 | 33 | 40 |
AFP, alfa fetoprotein; HBV, hepatitis B virus.
P < 0.05.