Table 1. Correlation between the clinicopathologic variables and SPC24 in HCC.
| Clinical character | Variable | No.of patients | SPC24 | χ2 | p-value | |
|---|---|---|---|---|---|---|
| low n (%) | high n (%) | |||||
| Age (years) | ≤60 | 167 | 44 (26.3) | 123 (73.7) | 0.116 | 0.733 |
| >60 | 45 | 13 (28.9) | 32 (71.1) | |||
| Gender | Female | 31 | 8 (25.8) | 23 (74.2) | 0.022 | 0.883 |
| Male | 181 | 49 (27.1) | 132 (72.9) | |||
| Family history | No | 177 | 44 (24.9) | 133 (75.1) | 2.243 | 0.134 |
| Yes | 35 | 13 (37.1) | 22 (62.9) | |||
| Wine-drinking | No | 100 | 24 (24.0) | 76 (76.0) | 0.802 | 0.370 |
| Yes | 112 | 33 (29.5) | 79 (70.5) | |||
| HBsAg | Negative | 37 | 8 (21.6) | 29 (78.4) | 0.632 | 0.427 |
| Positive | 175 | 49 (28.0) | 126 (72.0) | |||
| AFP (μg/l) | ≤200 | 95 | 32 (33.7) | 63 (66.3) | 4.046 | 0.044 |
| >200 | 117 | 25 (21.4) | 92 (78.6) | |||
| Median size (cm) | ≤5 | 52 | 20 (38.5) | 32 (61.5) | 4.696 | 0.030 |
| >5 | 160 | 37 (23.1) | 123 (76.9) | |||
| Cirrhosis | No | 20 | 7 (35.0) | 13 (65.0) | 0.739 | 0.390 |
| Yes | 192 | 50 (26.0) | 142 (74.0) | |||
| Tumor number | Single | 145 | 46 (31.7) | 99 (68.3) | 5.461 | 0.019 |
| Multiple | 67 | 11 (16.4) | 56 (83.6) | |||
| BCLC stage | 0-A | 101 | 35 (34.7) | 66 (65.3) | 5.919 | 0.015 |
| B–C | 111 | 22 (19.8) | 89 (80.2) | |||
| PVTT | No | 166 | 46 (27.7) | 120 (72.3) | 0.264 | 0.607 |
| Yes | 46 | 11 (23.9) | 35 (76.1) | |||
| Distant metastasis | No | 193 | 51 (26.4) | 142 (73.6) | 0.234 | 0.629 |
| Yes | 19 | 6 (31.6) | 13 (68.4) | |||
| Recurrence | No | 145 | 41 (28.3) | 104 (71.7) | 0.450 | 0.502 |
| Yes | 67 | 16 (23.9) | 51 (76.1) | |||
Abbreviations: HBsAg, hepatitis B surface antigen; AFP, alpha-fetoprotein; BCLC, Barcelona clinic liver cancer; PVTT, portal vein tumor thrombus.