Table 3.

Incidence of Withdrawal.

Mean number of WDS symptoms reported, and the percentage of women and men who reported experiencing each individual symptom among women (n=45) and men (n=91). Mean number of symptoms reported was compared between women and men using a t-test and percentage reporting individual symptoms were compared using Fisher’s exact tests. Significant (p < 0.05) sex differences are highlighted with bold text.

	Women (n=45)	Men (n=91)	p-value
mean (±SD) number of WDS symptoms reported	7.9 (3.3)	6.2 (3.2)	<0.01
depressed mood	76	64	0.12
irritability	89	73	0.05
nervousness/anxiety	51	51	1.00
restlessness	84	74	0.20
increased aggression	51	43	0.46
increased anger	60	53	0.07
violent outbursts	47	22	<0.01
nausea	40	7	<0.01
decreased appetite	73	67	0.56
stomach pain	22	10	0.07
shakiness	22	14	0.33
sweating	31	26	0.69
sleep difficulty	100	90	0.03
strange/wild dreams	47	40	0.46
craving to smoke cannabis *	100	96	0.30

Note. WDS = 14-item Withdrawal Discomfort Scale,

^*Craving is reported separately as it is not one of the symptoms included in the WDS total score.