Table 1.

Relationship between OMERACT RA Flare Core Domains and legacy PRO measures or joint counts by flare status^*

Domains		All	Physician**		Patient***		DAS28†
			Yes	No	Yes	No	Yes	No
N	Source	501	148	253	124	377	49	264
Pain
How much pain due to RA in past week	HAQ	0.91	0.87	0.91	0.87	0.88	0.83	0.90
Today’s level of pain today	RADAI	0.84	0.81	0.81	0.83	0.79	0.80	0.85
Pain past week	Pt Global	0.93	0.89	0.92	0.87	0.90	0.91	0.90
Joint area pain severity (0–48)	RADAI	0.72	0.65	0.70	0.59	0.69	0.51	0.75
Patient Tender joint count (40)	Patient	0.54	0.41	0.57	0.35	0.49	0.37	0.63
MD Tender joint count (28)	MD	0.50	0.33	0.50	0.29	0.43	0.29	0.51
Physical Function
Disability score (0–3)	HAQ	0.76	0.73	0.71	0.70	0.68	0.63	0.77
Physical Function	RAND-12	−0.68	−0.68	−0.61	−0.71	−0.60	−0.64	−0.67
Daily activities in past 7 days	WPAI	0.82	0.80	0.78	0.80	0.80	0.75	0.81
Fatigue
Vitality (Rand-12)	RAND-12	−0.62	−0.60	−0.65	−0.64	−0.59	−0.69	−0.61
Unusual fatigue/tiredness past week	Pt Global	0.88	0.81	0.88	0.78	0.87	0.81	0.89
Participation
Role – Physical	RAND-12	−0.72	−0.65	−0.71	−0.69	−0.66	−0.70	−0.67
Social Function	RAND-12	−0.61	−0.67	−0.60	−0.72	−0.49	−0.68	−0.61
Productivity while working	WPAI	0.79	0.83	0.82	0.84	0.74	0.77	0.79
RA affecting daily activities	WPAI	0.82	0.78	0.80	0.76	0.79	0.79	0.81
Stiffness
AM joint stiffness score	RADAI	0.68	0.58	0.65	0.52	0.64	0.57	0.71

^*Spearman correlation coefficients for second visit.

^**Physician endorsement of flare based on rating ≥ 0.5 cm on flare severity 100 mm VAS.

^***Patient classification of flare based on Yes/No.

^†DAS scores < 3.2 at second visit required an increase of 1.2 units whereas DAS ≥ 3.2 at second visit required increase of 0.6.

HAQ=Health Assessment Questionnaire-DI; RADAI=Rheumatoid Arthritis Disease Activity Index; Pt. Global=Patient Global Assessment of Disease Activity; VR-12=Veteran Rand-12 Health Survey; WPAI=Work Productivity and Activity Impairment-Rheumatoid Arthritis.