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. Author manuscript; available in PMC: 2016 Feb 9.
Published in final edited form as: Breast Cancer Res Treat. 2009 Sep 26;122(2):307–314. doi: 10.1007/s10549-009-0556-1

Figure 6.

Figure 6

NMDAR1 receptors influence on the growth of human breast cancer tumor xenografts in nu/nu mice. Administration of MK-801 in doses of 0.3 mg/kg twice daily for 10 days (days 0 through 9) completely prevented growth of MCF-7 xenografts (p<0.0001) while having no apparent impact on animal health. Shown as means ±SEM are values for control (■) and treated (□) animals. Tumor volume measured by micrometer was expressed as the product of length x width x depth and was evaluated on a daily basis, as was animal body weight.