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. 2016 Feb 9;11(2):e0148746. doi: 10.1371/journal.pone.0148746

Fig 3. Expression of putative mRNAs targeted of miR-146a-5p.

Fig 3

The relative mRNA expression levels of the potential miR-146a-5p targets BRCA1, MCM10, CDKN3, CXCL8/IL8, and UHRF1 were measured in duplicates in a pool of normal renal tissue and tissue samples from primary ccRCC-M0 and ccRCC-M1 patients by RT-qPCR. Data were normalized with PPIA reference gene [19], (S2 Fig). BRCA1, CDKN3, MCM10, CXCL8/IL8, and UHRF1 are lower in tissue samples of ccRCC without metastasis compared to ccRCC with metastasis.