Table 3. Analysis of saliva stimulated by Pilocarpine (1mg/Kg of b.w.) of Control, Sham and chronic kidney disease (CKD) groups at 8 and 12 weeks of experiment.
| 8 weeks | 12 weeks | |||||
|---|---|---|---|---|---|---|
| Control | Sham | CKD | Control | Sham | CKD | |
| Flow rate (μL/min) | 47.8 ± 11.4 (n = 9) | 54.4 ± 15.5 (n = 8) | 59.3 ± 14.8 (n = 9) | 39.0 ± 10.6 (n = 10) | 33.0 ± 9.5 (n = 9) | 34.7 ± 13.0 (n = 8) |
| Protein (mg/ml) | 0.98 ± 0.19 (n = 8) | 0.90 ± 0.24 (n = 8) | 1.04 ± 0.27 (n = 8) | 1.25 ± 0.32 (n = 10) | 1.42 ± 0.53 (n = 9) | 2.56 ± 2.13 * (n = 8) |
| Amylase (mg of maltose/mg protein) | 331 ± 80 (n = 9) | 436 ± 100 (n = 7) | 240 ± 142 # (n = 7) | 273 ± 84 (n = 10) | 234 ± 68 (n = 9) | 211 ± 133 (n = 8) |
| Peroxidase (μg/mg protein) | 1.47 ± 0.54 (n = 8) | 1.41 ± 0.66 (n = 8) | 1.50 ± 0.80 (n = 7) | 5.14 ± 3.14 (n = 10) | 5.96 ± 3.23 (n = 9) | 46.4 ± 34.9 * # (n = 8) |
| Salivary urea (mg/dL) | 51.47 ± 7.5 (n = 8) | 51.47 ± 6.2 (n = 8) | 105.1±25.67 * # (n = 8) | 42.86 ± 4.9 (n = 7) | 45.98 ± 6.51 (n = 7) | 93.49 ± 20.7 * # (n = 8) |
Values are expressed in mean ± SD. n = number of animals.
The * indicates differences from Control and # differences from Sham group (p<0.05), on the same experimental period.