Table 2. Evaluation of Ki67 and p21 staining in R26-AKT1E17K mice.
| Mouse code | Treatment | Ki67 positive nuclei | p21 positive nuclei | Mean of Ki67 positive nuclei | Mean of p21 positive nuclei |
|---|---|---|---|---|---|
| #2a | Vehicle | 2.3±1.8 | 0.7±1.7 | 4.6±0.49 | 2.4±0.4 |
| #4a | Vehicle | 6.2±2.4 | 1.5±1.3 | ||
| #5a | Vehicle | 5.5±2.1 | 5.2±1.8 | ||
| #7a | Ad-CRE | 21.4±10 | 2±1.5 | 11.1±1.2 | 2.8±0.5 |
| #8a | Ad-CRE | 6.1±2.4 | 6.6±5.8 | ||
| #10a | Ad-CRE | 6.2±4.3 | 2±1.0 | ||
| #11a | Ad-CRE | 16.4±6.4 | 2.4±2.2 | ||
| #12a | Ad-CRE | 7.5±1.9 | 1±1.2 |
Evaluation of Ki67 and p21 stainings was performed by counting positive nuclei in 10 fields at X400 magnification. (p<0.001; t-Student).