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. 2016 Feb 9;11(2):e0148819. doi: 10.1371/journal.pone.0148819

Fig 2. High-dose NaF impaired the proliferation and viability of hESCs.

Fig 2

(A) Proliferation of hESCs in the 2 mM NaF-treated group was significantly lower than in the untreated and 1 mM NaF-treated groups. (B) Cell cycle arrest in G0/G1 phase was induced in H9 hESCs after exposure to 2 and 4 mM NaF. (C) Cell viability of hESCs was dramatically decreased in the 2, 4 and 6 mM NaF-treated groups, with a time-dependent reduction in the 2 mM NaF-treated group. *, p < 0.05. **, p < 0.01. ***, p < 0.001.