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. 2016 Feb 9;10(2):e0004180. doi: 10.1371/journal.pntd.0004180

Fig 7. ISE6 proteins with increased expression associate with pathways for protein production, transport, assembly, and proteolysis.

Fig 7

The ISCW accession numbers corresponding to proteins identified with increased expression in LGTV-infected and UV-LGTV-treated cells are shown (KEGG abbreviated nomenclature provided as well if available in parentheses). The schematic presents potential mechanisms for LGTV-induced perturbation and increase in cell protein expression. See S5 Table for information on proteins and KEGG protein classes. Underlined proteins denote ISE6 proteins exhibiting increased expression following flavivirus infection not identified before. “Fld, Srt, & Deg” is the folding, sorting, and degradation KEGG pathway. ** denotes ortholog in human [19]; + denotes human ortholog showing increased expression following HCV infection;—denotes human ortholog showing decreased expression following HCV infection. Gray boxes denote cellular protein functions. White boxes denote KEGG pathways.