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. 2015 Dec 21;13(6):355–363. doi: 10.1016/j.gpb.2015.09.005

Figure 4.

Figure 4

Intrinsic curvature profiles around the TSPs for mutant rRNA genes promoters in T. cruzi

Intrinsic curvature for the core promoters of indicated rRNA genes in the 100-bp regions centered at the TSP in T. cruzi. A. Mutations at the transcription start region (see [27]). M16 (Construct 16) is a down-regulating mutant, whereas M17 (Construct 17) is an up-regulating mutant [27]. B. Four down-regulating point mutations at the transcription start region, M20–M23 (see [27]). The vertical dashed lines at +1 in both panels mark the position of the TSP. Curvature is expressed as degrees (deg.) per helical turn. TSP, transcription start point.