Supplementary Figure S1.

Average intrinsic curvature for core promoters of human RNAPII genes

The average intrinsic curvature for the core promoters of 35 random RNAPII-transcribed genes in the 100-bp regions centered at the TSP. Dots and vertical bars at each nucleotide position represent average curvature and standard deviation, respectively. See Materials and Methods for database identifiers. The vertical dashed line at +1 marks the position of the TSP. Curvature is expressed as degrees (deg.) per helical turn. TSP, transcription start point.