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Bisulfite sequencing analysis of representative CIMP and HIM genes in snap-frozen human samples. Bisulfite sequencing analysis of representative CIMP and HIM genes in snap-frozen matched adjacent normal (N) and BRAF-positive human melanoma tumor (T) samples is shown. (Upper) Schematic of each promoter; positions of CpGs are shown to scale by vertical lines. (Lower) Each circle represents a methylated (●) or unmethylated (○) CpG dinucleotide. Each row represents a single clone.
