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. 2016 Jan 19;113(5):1321–1326. doi: 10.1073/pnas.1515137113

Table S1.

Transcription factor binding sites found overrepresented in the promoters of genes with higher expression in the long-lived IIS mutant flies

TRANSFAC Drosophila TF binding to site Function summary
AP-1 Jra Kayak Cytoskeletal rearrangement in development, immune response, wound healing
DR1 PPAR ortholog unknown in flies Control aspects of fat tissue formation and metabolism in mammals
Evi-1 Putatively CG10348 and Hamlet Neuronal development
GATA Pnr, Srp, Grn, GATAd GATAe Hematopoeisis, cardiac development, endoderm development and adult immunity
HNF4 Hnf4 CNS development
Pbx Extradenticle Developmental leg patterning
PXR DHR96 Req for normal regulation of detox enzymes
TFAM mtTF A mitDNA replication and maintenance
TTF1 Putatively Vnd Ventral nerve system development
Zeste Zeste Regulation of homeotic genes
*

Known proteins or predicted orthologs of proteins binding to DNA element. See also Dataset S2.