Table 1. Demographic characteristics of SCD patient population.

	Alloimmunization status	Number of Patients	Mean ± SD	95% CI	P-value
Age (Years)†	Alloimmunized	83	17.2 ± 4.6	16.2 – 18.2	0.13*
	Non-alloimmunized	116	15.9 ± 5.5	14.9 – 16.9
Number of units of RBC transfusions	Alloimmunized	88	23 ± 38	22 – 24	<0.001**
	Non-alloimmunized	116	65 ± 83	64 – 67
Gender‡
Female	Alloimmunized	37			0.62^
	Non-alloimmunized	45
Male	Alloimmunized	45
	Non-alloimmunized	61

^†Data available from 188 patients;

^‡Data available from 199 patients

^*p value calculated by Wilcoxon rank sum test;

^**p value calculated by Poisson regression;

^{^}p value calculated by χ² test.

SCD, sickle cell disease; SD, Standard deviation; CI, confidence interval