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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Ann Surg. 2016 Mar;263(3):565–572. doi: 10.1097/SLA.0000000000001049

Figure 2.

Figure 2

Cell swelling of liver tissue slices in-vitro in response to hypoxic ischemia and the effects of various concentrations of cell impermeants on the cell swelling response. Cell swelling was indexed by measuring total tissue water (TTW) of the liver slices an hour after ischemia and an hour after normoxic reperfusion or in fresh controls. Cell impermeants were in the Krebs buffer suffusing the slices during ischemia. In general, the impermeant effect is proportional to the molecular weight of the impermeant and its concentration in the extracellular space. n=6 liver samples per group, values are mean ± SD. Each impermeant group also has a zero concentration control, which sees ischemia and reperfusion without any impermeants.