Table 1.
Genes appearing at the top network in MCF-7 with differential methylation by proton beam.
| Symbol | Accession | Description | Fold change |
|---|---|---|---|
| CASP8AP2 | NM_012115 | CASP8-associated protein 2 | 2.1 |
| CBX5 | NM_012117 | Chromobox homolog 5 (HP1 alpha homolog, Drosophila) | -2.2 |
| CENPA | NM_001809 | Centromere protein A | 2.3 |
| CEP97 | NM_024548 | Centrosomal protein 97kDa | -2.8 |
| COMMD1 | NM_016144 | Copper metabolism (Murr1) domain-containing 1 | 2.3 |
| ERMAP | NM_001017922 | Erythroblast membrane-associated protein | 2.7 |
| FAF1 | NM_007051 | Fas (TNFRSF6) associated factor 1 | 2.4 |
| FAM46A | NM_017633 | Family with sequence similarity 46, member A | 3.0 |
| GMFB | NM_004124 | Glia maturation factor, beta | 2.2 |
| GTF2B | NM_001514 | General transcription factor IIB | -2.7 |
| GTF2H4 | NM_001517 | General transcription factor IIH, polypeptide 4, 52kDa | 2.1 |
| HIST1H2AD | NM_021065 | Histone cluster 1, H2ad | 2.1 |
| HIST3H2A | NM_033445 | Histone cluster 3, H2a | -2.1 |
| HIST3H2BB | NM_175055 | Histone cluster 3, H2bb | -2.1 |
| HMGCL | NM_000191 | 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase | -2.3 |
| LRCH3 | NM_032773 | Leucine-rich repeats and calponin homology (CH) domain-containing 3 | 3.5 |
| NKIRAS2 | NM_001001349 | NFKB inhibitor interacting Ras-like 2 | 2.0 |
| RDM1 | NM_001163120 | RAD52 motif 1 | -2.2 |
| RPS10-NUDT3 | NM_001202470 | Ribosomal protein S10 and nucleoside diphosphate linked moiety X type motif 3 | 3.1 |
| RRAS | NM_006270 | Related RAS viral (r-ras) oncogene homolog | 2.7 |
| RSU1 | NM_012425 | Ras suppressor protein 1 (RSU1) | 2.2 |
| SLC2A12 | NM_145176 | Solute carrier family 2 (facilitated glucose transporter), member 12 | 2.2 |
| SLC37A4 | NM_001164280 | Solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 2.0 |
| SUGT1 | NM_006704 | SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) | 2.3 |
| SUPT20H | NM_001014286 | Family with sequence similarity 48, member A | 2.1 |
| TCEB3 | NM_003198 | Transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) | 2.1 |
| UBE2B | NM_003337 | Ubiquitin-conjugating enzyme E2B (RAD6 homolog) | 2.7 |
| YBX3 | NM_001145426 | Cold shock domain protein A | 2.2 |
| ZNF8 | NM_021089 | Zinc finger protein 8 | 2.5 |
| ZW10 | NM_004724 | ZW10, kinetochore associated, homolog (Drosophila) | 2.0 |