A: representative Western blots of natriuretic peptides ANP and BNP, α-SMA, and p- and t-SMAD2/3, ERK1/2, and p38 MAPK from WT and Dil and Con group Marfan HT mice at 6–14 mo of age. B and C: summary data for immunoblots: p/t ratio of ERK1/2 (B); and α-SMA, ANP, BNP, and p/t ratio of SMAD2/3 (C). Values are means ± SE; n = 3 per group. *P < 0.05 and **P < 0.01, WT vs. HT. #P < 0.05, Dil vs. Con.