Table 3.
Multivariate associations of renal blood flow (ml/min*1.73m2) measured by MRI or hippuran with characteristics indicative for disease severity in patients stratified for kidney function
| eGFR >70 ml/min*1.73m2 | MRI | Hippuran | ||
|---|---|---|---|---|
| N = 57 | Std β | p | Std β | p |
| Adjusted R2 | 0.36 | 0.51 | ||
| Age (years) | -0.26 | 0.07 | ||
| Female vs male sex (1 or 0) | -0.36 | 0.005 | ||
| Weight (kg) | -0.13 | 0.23 | -0.20 | 0.08 |
| Antihypertensive drugs (Yes = 1) | 0.19 | 0.01 | 0.17 | 0.11 |
| Plasma osmolality (mOsm/kg) | 0.14 | 0.20 | ||
| eGFR (ml/min*1.73m2) | 0.66 | <0.001 | 0.60 | <0.001 |
| 24h Urine volume (mL) | 0.12 | 0.30 | 0.28 | 0.02 |
| Ln (Urinary albumin excretion mg/24h) | 0.24 | 0.03 | 0.16 | 0.13 |
| eGFR ≤ 70 ml/min*1.73m2 | MRI | Hippuran | ||
| N = 34 | Std β | p | Std β | p |
| Adjusted R2 | 0.17* | 0.72* | ||
| Female vs male sex (1 or 0) | -0.30 | 0.15 | ||
| Weight (kg) | -0.21 | 0.24 | ||
| Plasma osmolality (mOsm/kg) | -0.23 | 0.20 | 0.10 | 0.31 |
| Log (Copeptin pmol/l) | -0.19 | 0.30 | -0.25 | 0.03 |
| eGFR (ml/min*1.73m2) | 0.38 | 0.03 | 0.89 | <0.001 |
| 24h Urine volume (mL) | -0.22 | 0.20 | -0.23 | 0.02 |
| Ln (Urinary albumin excretion mg/24h) | 0.17 | 0.14 | ||
* Model discrimination assessed by bootstrapping (2000 times), p-value < 0.001.