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SK channel currents across cell-attached basolateral membrane patches on crypts from normal sigmoid colon, in the basal state and after the addition of 10 μM forskolin (A) or (B) 1 μM TXA2. Recordings were obtained at a command potential (Vcom) of −100 mV (referenced to pipette interior), broken lines indicating closed channel currents and downward deflections indicating channel openings.
