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. 2016 Feb 10;7:10. doi: 10.3389/fgene.2016.00010

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Copyright © 2016 Lustig.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Proteomic view of Association of Cdc6 with both Orc1 and Sir3 Protein-based associations are present between Orc1 and other yeast nuclear factors. We conducted an SGD search for physical interactions between Orc1 or Sir3 and other cellular proteins using at least four experiments. Orc1 is capable of associating with Cdc6 while Sir3 is not. In no experiment was Cdc6/Sir3 binding observed. One genetic interaction between Orc3 and Orc6 is also shown in this figure.