Figure 7.

Model correctly predicts deficits in ectopic animals for auditory thalamic population responses to clicks following noise. All model parameters and plotting conventions as in Figure 6. a, Model predictions of responses to 50, 100, or 200 ms noise followed by click 20 ms after noise offset (left). Data testing these predictions (population PSTHs, right) were collected in experiments in 4 ectopic and 3 nonectopic animals. b, Zoomed-in view of population PSTHs during the 70 ms period following noise offset; click 20 ms after noise offset indicated by black dot below each trace. c, Left, Difference between peak “nonectopic” and “ectopic” model output for a simulated click 20 ms following noise, as a function of the duration of the noise. Right, Same analysis for ventral MGB data, showing mean ± SE of difference between peak nonectopic and ectopic population firing rates for a click following noise.