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. 2016 Feb 10;6:20932. doi: 10.1038/srep20932

Table 4. Accuracy of optimal thresholds for ischemic core (major reperfusion group).

Threshold (within delay time ≥ 3 s) Youden’s Index Sensitivity Specificity Mean magnitude (ml) r P value
rCBF ≤ 30% 0.40 0.64 0.76 10.8 0.881  < 0.001
CBF ≤ 6 ml/100 g/min 0.36 0.55 0.81 19.4 0.716  < 0.001
rCBV ≤ 50% 0.27 0.49 0.78 24.7 0.530  < 0.001
CBV ≤ 1 ml/100 g 0.26 0.40 0.86 22.5 0.566  < 0.001
Delay time ≥ 7 s 0.28 0.57 0.71 17.6 0.752  < 0.001
rMTT ≥ 200% 0.20 0.53 0.66 18.4 0.743  < 0.001
MTT ≥ 13 s 0.20 0.41 0.79 27.0 0.348 0.017

More data in supplemental material.

CBF, cerebral blood flow; CBV, cerebral blood volume; MTT, mean transient time.